How The mRNA Vaccines Were Made: Halting Progress and Happy Accidents – The New York Times:
The vaccines were possible only because of efforts in three areas. The first began more than 60 years ago with the discovery of mRNA, the genetic molecule that helps cells make proteins. A few decades later, two scientists in Pennsylvania decided to pursue what seemed like a pipe dream: using the molecule to command cells to make tiny pieces of viruses that would strengthen the immune system.
The second effort took place in the private sector, as biotechnology companies in Canada in the budding field of gene therapy — the modification or repair of genes to treat diseases — searched for a way to protect fragile genetic molecules so they could be safely delivered to human cells.
The third crucial line of inquiry began in the 1990s, when the U.S. government embarked on a multibillion-dollar quest to find a vaccine to prevent AIDS.
Early Vaccine Doubters Now Show a Willingness to Roll Up Their Sleeves – The New York Times:
The lure of the vaccines’ modest quantities also can’t be underestimated as a driver of desire, somewhat like the must-have frenzy generated by a limited-edition Christmas gift, according to public opinion experts.
… the grim reality of the pandemic — with more than 200,000 new cases and some 3,000 deaths daily — and the wanness of this holiday season are perhaps among the biggest factors.
Health Care Worker Had Serious Allergic Reaction After Pfizer’s Covid Vaccine – The New York Times:
the requirement that recipients remain in place for 15 minutes after getting the vaccine helped ensure the woman was quickly treated.
via Eric Topol on Twitter
Covid-19 Live Updates: Plans to Ship Vaccine Are Underway – The New York Times:
“With Pfizer’s vaccine cleared for emergency use on Friday, states eagerly began their own preparations to receive the vaccine within days. Up to 300,000 cases have been traced to a Boston Biogen conference in February.”
*This is an important next step.